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          當(dāng)前位置:首頁公司新聞Biomedica 公司NT-proBNP ELISA Kit 簡介

          Biomedica 公司NT-proBNP ELISA Kit 簡介

          更新時間:2014-03-23點擊次數(shù):1340

          NT-proBNP ELISA Kit (Cat.No.SK-1204)

          為什么要檢測NT-proBNP

          NT-proBNP proBNP分解后的76氨基酸片段。proBNP是心臟為彌補收縮無力而增大時,心壁被拉伸時由心臟釋放到血液中的化學(xué)物質(zhì)。一旦從心臟釋放到血液中,proBNP就會分割為NT-proBNPBNP。由于NT-proBNP的半衰期為120min,相比之下,BNP的半衰期僅20min。所以NT-proBNP可追蹤的時間可達24hBNPzui多可監(jiān)測的時間為1h。因此,檢測血清/血漿中的NT-proBNP穩(wěn)定性更好,檢測結(jié)果更可靠,是有效的心衰檢測工具。

          應(yīng)用領(lǐng)域:

          1. 心臟衰竭、急性心肌梗死(左心室功能不全)
          2. 腎衰竭
          3. 肥胖癥和糖尿病
          4. 各種形式的繼發(fā)性高血壓
          5. 心衰患者的療效監(jiān)測

          產(chǎn)品優(yōu)勢:

          1. 性價比高
          2. 可用于每個實驗室或開放實驗室
          3. CE 標(biāo)志-可用于臨床診斷
          4. 簡單-傳統(tǒng)96孔板
          5. 動態(tài)檢測范圍廣-可用于早期心衰檢測

          試劑盒特點:

          檢測方法:夾心ELISAHRP/TMB顯色,12x8 板條

          樣本類型:血清

          樣品量:50ul/test

          標(biāo)準(zhǔn)品范圍:0-640 pmol/L

          檢測靈敏度:3pmol/L

          孵育條件:3h/30min

          單位換算:1pmol/L=8.475pg/ml

          參考文獻:

          1

          Infliximab Treatment Increases Left Ventricular Ejection Fraction in Patients with Rheumatoid Arthritis: Assessment of Heart Function by Echocardiography, Endothelin 1, Interleukin 6, and NT-pro Brain Natriuretic Peptide. PRZEMYSLAW J,et al. J Rheumatol, Apr 2012; 39: 701 - 706.

          2

          Left Ventricular Function Impairment in Patients With Normal-Weight Obesity:

          Contribution of Abdominal Fat Deposition, Profibrotic State, Reduced Insulin

          Sensitivity, and Proinflammatory Activation. Wojciech Kosmala,et al. Circ Cardiovasc Imaging, May 2012; 5: 349 - 356.

          3

          Prognostic value of left atrial expansion index and exercise-induced change in atrial natriuretic peptide as long-term predictors of atrial fibrillation recurrence..Malini Govindan,et al. Europace, Sep 2012; 14: 1302 - 1310.

          4

          Osteopontin-mediated myocardial fibrosis in heart failure: a role for lysyl

          oxidase? Begoña López,et al. Cardiovasc Res, Jul 2013; 99: 111 - 120. 

          5

          High-sensitivity troponin assay improves prediction of cardiovascular risk in

          patients with cerebral ischaemia. Raoul Stahrenberg,et al. J. Neurol. Neurosurg. Psychiatry, May 2013; 84: 479 - 487.

          6

          Translational phases of evidence in a prognostic biomarker: a systematic review and meta-analysis of natriuretic peptides and the prognosis of stable coronary disease. Shailen Sutaria,et al. Heart, Apr 2012; 98: 615 - 622. 

          7

          Prognostic impact of body mass index in patients undergoing coronary artery

          bypass surgery. Shih-Hsien Sung,et al. Heart, Apr 2011; 97: 648 - 654.

          8

          Troponin T, N-terminal pro natriuretic peptide and a patent ductus arteriosus

          scoring system predict death before discharge or neurodevelopmental outcome at 2 years in preterm infants. Afif F EL-Khuffash,et al. Arch. Dis. Child. Fetal Neonatal Ed., Mar 2011; 96: F133 - F137. 

          9

          Multidimensional assessment of older people with asthma and COPD: clinical

          management and health status. Vanessa M. McDonald,et al. Age Ageing, Jan 2011; 40: 42 – 49

          10

          Diagnostic value of NT-proBNP in identifying aortic stenosis patients with heart failure. C Wu,et al. Zhonghua Xin Xue Guan Bing Za Zhi, Jul 2010; 38(7): 579-83.

          11

          Pulmonary arterial hypertension in rheumatic mitral stenosis: does it affect right

          ventricular function and outcome after mitral valve replacement? Shantanu Pande,et al. Interact CardioVasc Thorac Surg, Sep 2009; 9: 421 - 425

          12

          Pulmonary arterial hypertension in rheumatic mitral stenosis: does it affect right

          ventricular function and outcome after mitral valve replacement? Shantanu Pande,et al. Interactive CardioVascular and Thoracic Surgery, Sep 2009; 9: 421 - 425.

          13

          Effect of piboserod, a 5-HT4 serotonin receptor antagonist, on left ventricular

          function in patients with symptomatic heart failure. John K. Kjekshus,et al. Eur J Heart Fail, Aug 2009; 11: 771 – 778

          14

          Prevalence of Left Ventricular Diastolic Dysfunction in a General Population. Tatiana Kuznetsova,et al. Circ Heart Fail, Mar 2009; 2: 105 - 112.

           

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